From the Overarching Cancer Research and Development Ambitions Strategy 2021-31, we said we would: ‘Advance new treatments, interventions and care’
We have: Achieved key milestones for the Cardiff Cancer Research Partnership (CCRP)
In this period, we have:
Trial portfolio overview:
|
Stage |
Study Name |
Study Type |
Funding |
Cancer Type |
|
Open to recruitment |
MORAb-202 (ON HOLD) |
First in Human |
Commercial |
Solid - Gynaecological |
|
Monumental-6 |
Bi-specific |
Commercial |
Haem - Multiple Myeloma |
|
|
Trials in set up |
IOV-MEL-301 |
TILS - ATMP |
Commercial |
Solid - Melanoma |
|
ATTR 01 |
Oncolytic virus vaccine - ATMP (FIH/FIC) |
Commercial |
Solid tumour (PDAC, CRC, NSCLC, H&N, gastric, ovarian, urothial) |
|
|
Protocol 75276617ALE1001 |
Phase I/II First in Human |
Commercial |
Haem - Leukaemia |
|
|
ABBVIE M25-059 |
ABBV-383 - BCMA bispecific antibody (IV), Phase I/II |
Commercial |
Haem - Multiple Myeloma |
We have also: Welcomed exciting BioNTech vaccine trials within the CCRP trial portfolio
The Cancer Vaccine Launchpad Wales will come under the CCRP umbrella. This BioNTech – HCRW collaboration agreement is £600K over two years for clinical leadership time, delivery nurses, pharmacy, radiology, pathology time (CVUHB and VCC).
BioNTech trial portfolio overview:
|
Stage |
Study Name |
Study Type |
Funding |
Cancer Type |
|
Open to recruitment |
BNT113 |
ATMP mRNA vaccine |
Commercial |
H&N |
|
BNT 327-03 |
Next generation immune checkpoint modulators |
Commercial |
NSCLC 1L
|
|
|
BNT327-06 |
Next generation immune checkpoint modulators |
Commercial |
Solid - Lung |
|
|
DB-1303 |
Antibody drug conjugate |
Commercial |
Breast |
|
|
Trials in set up |
BNT116 |
First in Human - ATMP - BNT116 mRNA cancer vaccine |
Commercial |
Solid - Lung |
|
BNT 327-07 |
Phase II - Bispecific |
Commercial |
Lung |
|
|
BNT-326-01 |
Phase II IV Vaccine |
Commercial |
Solid - multi |